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Moore, Jason
University of Pennsylvania
Philadelphia, Pennsylvania
 
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Jason Moore is the Frank Lane Research Scholar in Computational Genetics and Director of Bioinformatics at Dartmouth Medical School, where he holds positions as Associate Professor of Genetics and Adjunct Associate Professor of Community and Family Medicine. He also holds positions as Affiliate Associate Professor of Computer Science at the University of New Hampshire and Adjunct Associate Professor of Computer Science at the University of Vermont. He was previously an Ingram Associate Professor of Cancer Research at Vanderbilt University Medical School, where he held positions as Assistant and Associate Professor of Molecular Physiology and Biophysics. He has won numerous awards including the James V. Neel Young Investigator award from the International Genetic Epidemiology Society and a Best Paper award from the ACM Genetic and Evolutionary Computing Conference (GECCO). He is currently Editor in Chief of a new journal, BioData Mining, that is published by BioMed Central.

Moore is a graduate of the University of Michigan in Ann Arbor, where he earned an MS in Human Genetics, an MA in Applied Statistics, and a PhD in Human Genetics. His dissertation work focused on computational and statistical methods for the genetic analysis of blood pressure change over a 24-hour period. He is also a graduate of Florida State University in Tallahassee, where he earned a BS in Biological Sciences.

His research focuses on the development, evaluation, and application of data mining and machine learning methods for the identification of genetic, genomic, and proteomic predictors of common human diseases, such as cancer and cardiovascular disease. Moore and his team have developed a number of novel machine learning methods, including multifactor dimensionality reduction (MDR) that uses constructive induction to detect nonlinear interactions among two or more attributes. He has published more than 150 peer-reviewed papers in journals and conference proceedings, and has delivered more than 100 invited lectures, including keynote lectures at the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology and the 2006 Annual Conference on the Mathematics of Information Technology and Complex Systems. More information about Moore and his work can be found at www.epistasis.org.

 
 
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   A vision for heart rate health through wearables
Albaghli R., Anderson K.  UbiComp 2016 (Proceedings of the 2016 ACM International Joint Conference on Pervasive and Ubiquitous Computing, Heidelberg, Germany, Sep 12-16, 2016) 1101-1105, 2016.  Type: Proceedings

Mobile health (mHealth) is an increasingly important area of biomedical informatics that is focused on the use of wearable sensors, such as those found in smartphones, to monitor health. This is an exciting area because of the widespre...

Oct 19 2016  
   Tractome: a visual data mining tool for brain connectivity analysis
Porro-Muñoz D., Olivetti E., Sharmin N., Nguyen T., Garyfallidis E., Avesani P. Data Mining and Knowledge Discovery 29(5): 1258-1279, 2015.  Type: Article

Brain imaging has revolutionized neuroscience and related areas such as neurogenetics by providing detailed measures of brain structure and function that can be used to advance our understanding of neuroanatomy and neurophysiology. Thi...

Oct 21 2015  
   Identifying biologically relevant genes via multiple heterogeneous data sources
Zhao Z., Wang J., Liu H., Ye J., Chang Y.  Knowledge discovery and data mining (Proceeding of the 14th ACM SIGKDD International Conference on Knowledge Discovery and Data Mining, Las Vegas, Nevada, Aug 24-27, 2008) 839-847, 2008.  Type: Proceedings

It is an exciting time in the biomedical sciences, given the availability of cutting-edge technology for measuring information about every gene in the human genome. Some of the computational challenges of identifying which of the many ...

Nov 6 2008  
   Consensus genetic maps as median orders from inconsistent sources
Jackson B., Schnable P., Aluru S. IEEE/ACM Transactions on Computational Biology and Bioinformatics 5(2): 161-171, 2008.  Type: Article

Two genes or genetic markers are said to be linked if they occur on the same chromosome and tend to be inherited together. The physical ordering of the genetic markers along the chromosome is called a genetic map. Alfred Sturtevant cre...

Oct 2 2008  
   Multiclass cancer classification using semisupervised ellipsoid ARTMAP and particle swarm optimization with gene expression data
Xu R., Anagnostopoulos G., Wunsch D. IEEE/ACM Transactions on Computational Biology and Bioinformatics 4(1): 65-77, 2007.  Type: Article

An important objective in clinical oncology is to rapidly determine the type of tumor a patient has, and to provide a prediction of tumor behavior in order to identify the most appropriate treatment. Traditionally, this has been done b...

Sep 5 2007  
 
 
   
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