Computing Reviews
Today's Issue Hot Topics Search Browse Recommended My Account Log In
Review Help
Molecular computers for molecular robots as hybrid systems
Hagiya M., Aubert-Kato N., Wang S., Kobayashi S. Theoretical Computer Science632 4-20,2016.Type:Article
Date Reviewed: May 2 2017

DNA computing is expanding its scope from mere DNA-based computing representation to developing integrated systems based on such computing. These integrated systems are called hybrid systems, and they are based on molecular computers, more precisely, molecular robots. This paper discusses molecular robots.

The authors examine the requirements of molecular computers in molecular robots, namely reactiveness, statefulness, hybridness, and persistency. They further find the components of a hybrid automaton, such as real-valued variables, discrete states (also called control modes), and discrete transitions (also called jumps). Furthermore, the authors describe the workflow of a hybrid automaton in the following three steps: identifying the inputs from the environment, designing the modes of the controller, and designing the transitions.

The authors describe the chemotaxis controller as an example hybrid controller implementing the following sections, input signal, the states of the controller, clock transitions, nonclock transitions, and domain-level implementation. The authors report two drawbacks in the existing DNA computing frameworks: “state transitions are not as sharp as expected for hybrid automata, and jump conditions require high Hill coefficients.”

This is an interesting read for nanotechnologists, professionals, and research scientists working in the areas of DNA computing, molecular computers, and robots. The description about using liposomes for jump transitions makes this paper worth reading. For future insights, the authors stress developing hybrid systems capable of implementing chemical reactions and physical phenomena in molecular robots. They further propose combining multiple approaches--whiplash machines, dynamic systems, and strand displacement reactions--while developing molecular robots.

Reviewer:  Lalit Saxena Review #: CR145238 (1707-0453)
Bookmark and Share
Heterogeneous (Hybrid) Systems (C.1.3 ... )
Robotics (I.2.9 )
Physical Sciences And Engineering (J.2 )
Would you recommend this review?
Other reviews under "Heterogeneous (Hybrid) Systems": Date
 Computationally intelligent hybrid systems: the fusion of soft computing and hard computing
Ovaska S., Wiley-IEEE Press, 2004. Type: Book (9780471476689)
Jun 10 2005
A high performance, low complexity algorithm for compile-time task scheduling in heterogeneous systems
Hagras T., Janeček J. Parallel Computing 31(7): 653-670, 2005. Type: Article
Aug 8 2006
On the efficacy of GPU-integrated MPI for scientific applications
Aji A., Panwar L., Ji F., Chabbi M., Murthy K., Balaji P., Bisset K., Dinan J., Feng W., Mellor-Crummey J., Ma X., Thakur R.  HPDC 2013 (Proceedings of the 22nd International Symposium on High-Performance Parallel and Distributed Computing, New York, NY, Jun 17-21, 2013)191-202, 2013. Type: Proceedings
Nov 14 2013

E-Mail This Printer-Friendly
Send Your Comments
Contact Us
Reproduction in whole or in part without permission is prohibited.   Copyright 1999-2024 ThinkLoud®
Terms of Use
| Privacy Policy